Drugs / Otezla
Otezla cost
apremilast · Amgen. Every official price for Otezla, side by side, with who pays it.
Short answer
On TrumpRx.gov, Amgen lists Otezla 30 mg (60 tablets) at $3,353.93 self-pay; the listing shows $5,589.89 as the wholesale acquisition cost. Medicare's negotiated price will be $1,650 for a 30-day supply from January 1, 2027. Pharmacies paid an average of $89.95–$181.20 per tablet (NADAC, Oct 21, 2026). In Medicare Part D, the yearly out-of-pocket limit is $2,100 in 2026 and $2,400 in 2027.12345
Source: TrumpRx.gov, CMS, data.medicaid.gov (NADAC) and Medicare.gov · checked Oct 23, 2026
Every official price
| Price | Amount | What it is | Date |
|---|---|---|---|
| Maker's list price (WAC) | $5,589.891 | For 60 tablets of 30 mg. The TrumpRx listing labels this the wholesale acquisition cost. | Oct 23, 2026 |
| Maker's self-pay price on TrumpRx | $3,353.931 | For 60 tablets of 30 mg, paying without insurance through the maker's channel listed on TrumpRx.gov. | Oct 23, 2026 |
| Medicare negotiated price | $1,6502 | For a 30-day supply, under Medicare's drug price negotiation, for Part D. The drug company must make it available to pharmacies that fill it for people with Medicare.7 | From Jan 1, 2027 |
| List price CMS compared it with | $4,7222 | The 2024 list price for a 30-day supply, in CMS's table. | 2024 |
| Pharmacy acquisition cost (NADAC) Otezla 10-20-30 mg start 28 day | $98.763 | Per pen or syringe. The national average price pharmacies pay to buy it. | Oct 21, 2026 |
| Pharmacy acquisition cost (NADAC) Otezla 20 mg tablet | $89.953 | Per tablet. The national average price pharmacies pay to buy it. | Jan 7, 2026 |
| Pharmacy acquisition cost (NADAC) Otezla 30 mg tablet | $90.593 | Per tablet. The national average price pharmacies pay to buy it. | Oct 21, 2026 |
| Pharmacy acquisition cost (NADAC) Otezla XR 75 mg tablet | $181.203 | Per tablet. The national average price pharmacies pay to buy it. | Oct 21, 2026 |
These are prices the drug company, Medicare and pharmacies use. What you pay depends on your coverage; see below.
With Medicare
- When filled at a pharmacy under a Part D plan, Part D's yearly out-of-pocket limit is $2,100 in 20264 and $2,400 in 2027.5 The standard Part D deductible is $700 in 2027.6 Your plan's own deductible and copays can be lower.
- The negotiated price starts on January 1, 2027; until then, the plan's usual price applies.2
- Higher income? Part B and Part D premiums can include IRMAA: IRMAA brackets.
With commercial insurance or no insurance
- What you pay depends on your plan's copay or coinsurance. The maker lists its savings and support options here: Amgen: Otezla cost and copay. We link to it but do not copy its terms.
Which drug, which dose, and whether to start, stop or switch are medical decisions. Ask your doctor or pharmacist.
Get an email when a price or rule changes
Only when an official GLP-1 self-pay price or a Medicare or Medicaid rule changes, at most once a week, with the official source for every change.
Official sources for this page (7)
- TrumpRx.gov: Otezla listing · as of Oct 23, 2026
“Otezla; Otezla XR Amgen Inc. Oral ulcers in Behçet’s Disease; Plaque psoriasis; Psoriatic arthritis $1,650 $4,722 65%”
- data.medicaid.gov: NADAC (National Average Drug Acquisition Cost) 2026 · as of Oct 23, 2026
“Out-of-pocket limit Yearly $2,100 (in 2026).”
Medicare.gov: Medicare costs · as of Oct 23, 2026“Out-of-Pocket Threshold: $2,100 Out-of-Pocket Threshold: $2,400”
CMS: CY 2027 Medicare Advantage and Part D Rate Announcement (Table V-6) · as of Oct 23, 2026“Deductible: $615 Deductible: $700”
CMS: CY 2027 Medicare Advantage and Part D Rate Announcement (Table V-6) · as of Oct 23, 2026“A participating drug company with a selected drug is required to ensure the negotiated price is made available to eligible individuals and to the pharmacies, mail-order services, and other entities that dispense the selected drug to such individuals.”